SKIPOGH stands for the Swiss Kidney Project on Genes in Hypertension; its aim is to explore the role of genetics and the environment (nutrition, physical activity, and way of life) on blood pressure regulation and kidney function. SKIPOGH will also increase the knowledge on the health status of inhabitants from Lausanne, Geneva and Bern, and allow scientists to assess to what degree parameters such as blood pressure, kidney size and function, body weight, and metabolism are inherited. The SKIPOGH study is embedded in the EPOGH study (European Project on Genes in Hypertension), an international cohort exploring the genetic determinants of blood pressure (BP) in the general population, and follows largely the same standardized protocol.