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More than 7000 persons have participated to EPOGH in Europe. This project was initiated by Prof. Jan Staessen (Catholic University of Leuven Belgium). EPOGH has resulted in over 100 scientific publications in the field of hypertension (high blood pressure) and genetics. It has substantially participated to the breakthrough established in 2009 in high blood pressure research, identifying 13 loci (regions of the chromosome) that are associated with high blood pressure. Of note, one of the SKIPOGH-investigators was first author of this paper.

The goal of SKIPOGH is to screen 1200 Swiss inhabitants, from approximately 400 families. A simple, non stratified sample of subjects has been drawn from lists of inhabitants provided by the population registers of the three cities. A letter inviting the addressee to participate is sent, and subjects are contacted within 14 days by one of the staff members. The following inclusion criteria are applied: (a) written informed consent; (b) minimum age 18 years; (c) willingness to take part in the examination and donate blood sample; (d) Caucasian origin, defined as having both parents and grandparents born in a restricted list of countries (available from the authors) (e) at least one, and preferably three, first degree family members also willing to participate. The family members are contacted in a similar way, and an appointment for a study visit is set individually with each family member. The SKIPOGH study was approved by the Institutional Ethics Committee of the Universities of Bern, Geneva and Lausanne. SKIPOGH has started recruitment in January 2010. In July 2011, a total number of 600 persons was reached. Recruitment shall continue until April 2013.

The SKIPOGH study has 4 field centers (Lausanne, Geneva, Bern, Zurich) and the data coordinating center in Lausanne.

The European Coordinating Center is in Leuven under the direction of Prof. Staessen.

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